1.  

Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. https://www.nature.com/articles/s41598-017-08392-1.pdf

2. 

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182158/

3. 

Do antibiotics cause mitochondrial and immune cell dysfunction? A literature review

https://www.researchgate.net/publication/358853910_Do_antibiotics_cause_mitochondrial_and_immune_cell_dysfunction_A_literature_review 

All scientific publications since the 1980’s related to the following fluoroquinolone side effects have been largely ignored by the authorities: DNA damage; mitochondrial damage; accumulation of fluoroquinolones in cells; nervous system damage; psychiatric disorders; reproductive defects; chromosomal abnormality, collagen destruction; aneurysms; HIF degradation; multi organ failure due to UGT, SULT and MRP 2 mutations; cytotoxicity; genotoxicity; diabetes; muscle atrophy; P450/CYP 2E1 dysfunction. Please see our compilation of scientific studies  related to the above, in addition to what is on this page:

Chemical proteomics reveal human off-targets of fluoroquinolone induced mitochondrial toxicity https://chemrxiv.org/engage/chemrxiv/article-details/67165e8712ff75c3a1142bb7

Multifocal dystonia induced by levofloxacin

https://www.researchgate.net/publication/323218012_Multifocal_dystonia_induced_by_levofloxacin

The effects of ciprofloxacin on male rabbits: Biochemical and histopathological study

https://www.iasj.net/iasj?func=fulltext&aId=112481

Chromosomal aberrations in human lymphocytes exposed in vitro to enrofloxacin and ciprofloxacin 

https://pubmed.ncbi.nlm.nih.gov/10048748/

Cytotoxic and genotoxic effects induced by enrofloxacin-based antibiotic formulation Floxagen ® in two experimental models of bovine cells in vitro: peripheral lymphocytes and cumulus cells 

https://pubmed.ncbi.nlm.nih.gov/30506381/

Fluoroquinolones are a potent form of chemotherapy

https://onlinelibrary.wiley.com/doi/10.1111/cxo.13102?fbclid=IwAR1lpP-fn8CLVm11ZU--oEdH8BbdFWRKugYA5tFK50icOEQhsa3oz2azqEE

Adverse drug reactions related to the use of fluorquinolone antimicrobials https://www.academia.edu/3597216/Adverse_drug_reactions_related_to_the_use_of_fluoroquinolone_antimicrobials?email_work_card=title

Fluoroquinolone-induced serious, persistent, multisymptom adverse effects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600819/ 

4-Quinolone Drugs Affect Cell Cycle Progression and Function of Human Lymphocytes In Vitro

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC174830/pdf/aac00096-0128.pdf

A comparative analysis of chromosomal aberrations in cultured human lymphocytes due to fluoroquinolone drugs at different expression periods https://www.researchgate.net/publication/40848285

Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages https://www.ncbi.nlm.nih.gov/pubmed/21764262

Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf

Pharmacokinetic prediction of levofloxacin accumulation in tissue and its association to tendinopathy

https://www.researchgate.net/publication/261759355

Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/pdf/nihms-509241.pdf

Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells https://www.ncbi.nlm.nih.gov/pubmed/8913349

Genotoxicity of topoisomerase II inhibitors: an anti-infective perspective

https://www.ncbi.nlm.nih.gov/pubmed/18840496

High-content screening for compounds that affect mtDNA-encoded protein levels in eukaryotic cells

https://www.ncbi.nlm.nih.gov/pubmed/20625181

Role of Mitochondria in Ciprofloxacin-Induced Apoptosis in Murine Sperm Cells

http://eprints.umsu.ac.ir/786/1/1933719113477482.pdf

Genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro

http://nmcth.edu/images/gallery/Editorial/xRZVmps_ambulkar.pdf

Exploration of the neurotoxicity of ciprofloxcin or gatifloxacin single dose in rat cortex and hippocampus

http://www.academicjournals.org/article/article1423846203_Arafa%20et%20al.pdf

Risk of hepatotoxicity associated with fluoroquinolones: A national case–control safety study

https://academic.oup.com/ajhp/article-abstract/71/1/37/5110881?redirectedFrom=fulltext&login=false&fbclid=IwAR0BBHVqCPEl3cy8pQrckDy4V7F1-3XaexO10zm15PTdLr5L4GJe7iYqjg8

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