• Home
  • About Us
  • Fluoroquinolones
    • FDA Warnings
    • EMA Warnings
    • Toxicity Warnings
    • Drug List
    • Chemical Composition
    • Library A-M
    • Library N-Z
    • Most Important Studies
  • Our Research
    • Our Sponsored Research
    • Supporting Studies
  • Find Help
  • Contact Us
  • Disclaimer
  • More
    • Home
    • About Us
    • Fluoroquinolones
      • FDA Warnings
      • EMA Warnings
      • Toxicity Warnings
      • Drug List
      • Chemical Composition
      • Library A-M
      • Library N-Z
      • Most Important Studies
    • Our Research
      • Our Sponsored Research
      • Supporting Studies
    • Find Help
    • Contact Us
    • Disclaimer
  • Home
  • About Us
  • Fluoroquinolones
  • Our Research
  • Find Help
  • Contact Us
  • Disclaimer

Fluoroquinolone Toxicity Study, NFP

Fluoroquinolone Toxicity Study, NFPFluoroquinolone Toxicity Study, NFPFluoroquinolone Toxicity Study, NFP

Top Supporting Studies To Our Work

1.  Németh et al. Aug 15, 2017.  Scientific Reports.  Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA. https://www.nature.com/articles/s41598-017-08392-1.pdf

Németh, Orgovan, Sódar, Osteikoetxea, Pálóczi, Szabó-Taylor, Vukman, Kittel, Turiák, Wiener, Tóth, Drahos, Vékey, Horvath & Buzás


2. Hangas et al.  Oct 12, 2018. Nucleic Acids Research, Volume 46, Issue 18.

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182158/

Hangas, Aasumets, Kekäläinen, Paloheinä, Pohjoismäki, Gerhold & Goffar


All scientific publications since the 1980’s related to the following Fluoroquinolone side effects have been largely ignored by the authorities: DNA damage; mitochondrial damage; accumulation of Fluoroquinolones in cells; nervous system damage; psychiatric disorders; reproductive defects; chromosomal abnormality, collagen destruction; aneurysms; HIF degradation; multi organ failure due to UGT, SULT and MRP 2 mutations; cytotoxicity; genotoxicity; diabetes; muscle atrophy; P450/CYP 2E1 dysfunction. Please see our compilation of scientific studies  related to the above, in addition to what is on this page:

  

Multifocal dystonia induced by levofloxacin

https://www.researchgate.net/publication/323218012_Multifocal_dystonia_induced_by_levofloxacin


The effects of ciprofloxacin on male rabbits: Biochemical and histopathological study

https://www.iasj.net/iasj?func=fulltext&aId=112481


Chromosomal aberrations in human lymphocytes exposed in vitro to enrofloxacin and ciprofloxacin 

https://pubmed.ncbi.nlm.nih.gov/10048748/


Cytotoxic and genotoxic effects induced by enrofloxacin-based antibiotic formulation Floxagen ® in two experimental models of bovine cells in vitro: peripheral lymphocytes and cumulus cells 

https://pubmed.ncbi.nlm.nih.gov/30506381/


Fluoroquinolones are a potent form of chemotherapy

https://onlinelibrary.wiley.com/doi/10.1111/cxo.13102?fbclid=IwAR1lpP-fn8CLVm11ZU--oEdH8BbdFWRKugYA5tFK50icOEQhsa3oz2azqEE


Adverse drug reactions related to the use of fluorquinolone antimicrobials https://www.academia.edu/3597216/Adverse_drug_reactions_related_to_the_use_of_fluoroquinolone_antimicrobials?email_work_card=title

  

Fluoroquinolone-induced serious, persistent, multisymptom adverse effects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600819/ 


4-Quinolone Drugs Affect Cell Cycle Progression and Function of Human Lymphocytes In Vitro

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC174830/pdf/aac00096-0128.pdf


A comparative analysis of chromosomal aberrations in cultured human lymphocytes due to fluoroquinolone drugs at different expression periods https://www.researchgate.net/publication/40848285


Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages https://www.ncbi.nlm.nih.gov/pubmed/21764262


Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf


Pharmacokinetic prediction of levofloxacin accumulation in tissue and its association to tendinopathy

https://www.researchgate.net/publication/261759355


Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/pdf/nihms-509241.pdf


Delayed cytotoxicity and cleavage of mitochondrial DNA in ciprofloxacin-treated mammalian cells https://www.ncbi.nlm.nih.gov/pubmed/8913349


Genotoxicity of topoisomerase II inhibitors: an anti-infective perspective

https://www.ncbi.nlm.nih.gov/pubmed/18840496


High-content screening for compounds that affect mtDNA-encoded protein levels in eukaryotic cells

https://www.ncbi.nlm.nih.gov/pubmed/20625181


Role of Mitochondria in Ciprofloxacin-Induced Apoptosis in Murine Sperm Cells

http://eprints.umsu.ac.ir/786/1/1933719113477482.pdf


Genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro

http://nmcth.edu/images/gallery/Editorial/xRZVmps_ambulkar.pdf


Exploration of the neurotoxicity of ciprofloxcin or gatifloxacin single dose in rat cortex and hippocampus

http://www.academicjournals.org/article/article1423846203_Arafa%20et%20al.pdf

  



DNA STRAND

Connect With Us

Help Our Cause

 Your support and contributions will help fund our latest research study currently in process.  

Pay with PayPal or a debit/credit card
  • About Us
  • FDA Warnings
  • EMA Warnings
  • Toxicity Warnings
  • Drug List
  • Chemical Composition
  • Library A-M
  • Library N-Z
  • Most Important Studies
  • Our Sponsored Research
  • Supporting Studies
  • Find Help
  • Contact Us

Copyright © 2020  - All Rights Reserved.

Powered by GoDaddy Website Builder