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This library features hundreds of global scientific publications related to fluoroquinolones, quinolones, and DNA, organized by category. Journal websites, articles, and PDF links may change over time. If a link does not open, please search the study title, DOI, PMID, or author names in PubMed or Google Scholar.
NEPHROPATHY
Allergic Nephropathy Associated with Norfloxacin and Ciprofloxacin
https://www.tandfonline.com/doi/abs/10.3109/00365599709030647?journalCode=isju19
NEURAL
Fluorinated 4-quinolones induce hyperproduction of interleukin 2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC287008/pdf/pnas00248-0298.pdf
Adverse Drug Reactions Related to the
Ciprofloxacin induced neurotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25902267
Effect of ciprofloxacin and levofloxacin on some oxidative stress parameters in brain regions
https://academicjournals.org/journal/AJPP/article-full-text-pdf/8C4F9F532018
Fluoroquinolone-related neuropsychiatric
https://www.ncbi.nlm.nih.gov/pubmed/26955658
Determination of the Excitatory Potencies of Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105691/pdf/ac001831.pdf
Effects of Novel 6-Desfluoroquinolones and Classic Quinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC89352/pdf/ac001729.pdf
Effects of sparfloxacin on CNS functions
https://www.ncbi.nlm.nih.gov/pubmed/16701999
Fluoroquinolones induced suicidal ideation
http://www.sciencedirect.com/science/article/pii/S0163834309000486?via%3Dihub
Possible Intermolecular Interaction between Quinolones and Biphenylacetic Acid Inhibit sy-Amino butyric Acid Receptor Sites
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC284738/pdf/aac00374-0093.pdf
Levofloxacin-induced Myasthenic Crisis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564188/pdf/662.pdf
Gemifloxacin-Associated Neurotoxicity Presenting
Permanent Peripheral Neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528905/pdf/10.1177_2324709614545225.pdf
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613252/pdf/dme0025-0856.pdf
Levofloxacin-induced myasthenic crisis
http://www.jem-journal.com/article/S0736-4679(12)01199-7/abstract
https://www.ncbi.nlm.nih.gov/pubmed/23218195
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564188/pdf/662.pdf
Exploration of neurotoxicity of ciprofloxacin or gatofloxacin
https://academicjournals.org/journal/AJPP/article-full-text/4BCF40A50432
Peripheral Neuropathy Associated with Fluoroquinolones
https://pubmed.ncbi.nlm.nih.gov/1352007/
Peripheral sensory disturbances related to treatment with Fluoroquinolones
Possible interaction of fluoroquinolones with GABA
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368276/pdf/brjclinpharm00069-0066.pdf
Quinolone antibiotics and suicidal behavior analysis
https://www.ncbi.nlm.nih.gov/pubmed/27113226
Potential Interactions CNS
https://link.springer.com/article/10.2165/00002018-199921020-00005
Quinolones review of psychiatric and neurological adverse reactions
Unexpected, severe central nerve system toxicity of
https://www.ncbi.nlm.nih.gov/pubmed/17268904
Safety issues and drug—drug
https://www.ncbi.nlm.nih.gov/pubmed/25423877
The neuroprotective role of Nigella sativa extract on
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
The Role of Mitochondria in Brain Aging and the Effects of Melatonin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001212/pdf/CN-8-182.pdf
Third and Fourth Generation Fluoroquinolone
https://www.ncbi.nlm.nih.gov/pubmed/24410307
Antibiotic-Induced Neurotoxicity
Convulsant and Subconvulsant Doses of Norfloxacin in the Presence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC127025/pdf/0301.pdf
Enhanced susceptibility of pentylenetetrazole kindled mice to quinolone effects
https://www.sciencedirect.com/science/article/abs/pii/S0924857999000679
Evaluation of the Possible Epileptogenic Activity of Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pubmed/23086472
Fluoroquinolone treatment alters the peptidergic innervation of rat salivary
http://onlinelibrary.wiley.com/doi/10.1002/ar.21037/full
Hippocampal Activity in the Presence of Quinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC284301/pdf/aac00376-0152.pdf
In Vitro Modulation of Hippocampal Pyramidal Cell Response
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC163578/pdf/402573.pdf
Effect of fluoroquinolones for Anticonvulsant activities on PTZ induced seizures
http://www.journalijar.com/uploads/2013-11-01_111226_981.pdf
Fluoroquinolone toxicity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981197/pdf/cp-2012-4-e87.pdf
Hereditary Neuropathy Unmasked by Levofloxacin
https://fqresearch.org/pdf_files/hereditary-neuropathy-unmasked-by-levaquin.pdf
A pharmacokinetic/pharmacodynamic approach to show that not all fluoroquinolones exhibit similar sensitivity toward the proconvulsant effect of biphenyl acetic acid in rats
https://academic.oup.com/jac/article/48/6/813/743793
Adverse Reactions to Fluoroquinolones. An Overview on Mechanistic Aspects
Treatment of the Fluoroquinolone Associated Disability –
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632915/pdf/OMCL2017-8023935.pdf
https://www.hindawi.com/journals/omcl/2017/8023935/
Effect of Bile Duct Ligation and Unilateral Nephrectomy on Brain Concentration and Convulsant Potential of the Quinolone
https://academic.oup.com/toxsci/article/29/2/280/1623527
Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots
http://www.sciencedirect.com/science/article/pii/S0301008215300605?via%3Dihub
https://www.ncbi.nlm.nih.gov/pubmed/26603930?dopt=AbstractPlus
Neuropsychiatric reactions to drugs an analysis of spontaneous
https://www.ncbi.nlm.nih.gov/pubmed/15661570
Oral fluoroquinolones and risk of secondary pseudotumor cerebri syndrome
http://n.neurology.org/content/early/2017/07/28/WNL.0000000000004247.short
Peripheral neuropathy and Guillain-Barré
https://www.ncbi.nlm.nih.gov/pubmed/24472364
https://www.sciencedirect.com/science/article/pii/S1047279713004754
Proteins from Human Cerebrospinal Fluid
http://science.sciencemag.org/content/182/4109/296
Effect of Ciprofloxacin Injection on Genetically Absence Prone (Wag/Rij) Rat's Electroencephalogram Characteristics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202555/pdf/BCN-4-031.pdf
The effect of levofloxacin and moxifloxacin on cardiovascular
https://www.ncbi.nlm.nih.gov/pubmed/22621918
Association of a Tourette-like Syndrome with Sparfloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034196/pdf/main.pdf
Levaquin induced acute psychosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/?report=printable
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/
Safety of fluoroquinolones update
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094848/pdf/JID13054.pdf
Reversible craniocervical dystonia associated with
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710986/pdf/40734_2015_Article_21.pdf
Ch 16 - The Quinolones: Prospects
https://www.sciencedirect.com/science/article/pii/B9780120595174500179
Anxiogenic and proconvulsant effect of gatifloxacin in mice
https://www.ncbi.nlm.nih.gov/pubmed/18022617
http://www.sciencedirect.com/science/article/pii/S001429990701196X
Generalized Seizure and Toxic Epidermal Necrolysis Following
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Fluoroquinolone –Induced Suicidal Ideation and Suicidality
http://www.psychosomaticsjournal.com/article/S0033-3182(11)00213-1/fulltext
Possible involvement of DEC1 on the adverse effects of quinolone antibiotics
http://www.myquinstory.info/wp-content/uploads/2010/01/Shi-2010-DEC1.pdf
https://www.ncbi.nlm.nih.gov/pubmed/2021494
Neuropsychological Side Effects Associated with Fluoroquinolone Therapy: A Qualitative Review with Recommendations for Future Research
https://www.medicalandresearch.com/assets/articles/documents/DOCUMENT_20220203153039.pdf
A VigiBase Descriptive Study of Fluoroquinolone-Associated Peripheral Nervous System Disorders https://mdpi-res.com/d_attachment/pharmaceuticals/pharmaceuticals-15-00143/article_deploy/pharmaceuticals-15-00143.pdf
NM NUCLEAR MEDICINE
Analytical methods for determination of new fluoroquinolones in biological matrices
https://link.springer.com/article/10.1007/s00216-011-5706-8
Ciprofloxacin is an inhibitor of the Mcm2-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/pdf/bsr033e072.pdf
Synthesis, characterization, antimicrobial
https://link.springer.com/article/10.1007/s00706-015-1507-7
A comparative analysis of chromosomal aberrations in cultured human lymphocytes https://link.springer.com/article/10.1007/s00204-009-0509-9
Fluoroquinolone-Associated Movement Disorder: A Literature Review
OCULAR
Phototoxic Lesions Induced by Quinolone
https://www.ncbi.nlm.nih.gov/pubmed/8052802
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells
https://www.sciencedirect.com/science/article/pii/S0014483521004231
2015 Effect of norfloxacin and moxifloxacin on melanin synthesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315488/pdf/11010_2014_Article_2297.pdf
Adverse Effects of Antimicrobials via Predictable or Idiosyncratic effects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421593/pdf/zac4046.pdf
Association Between Recent Use of fluoroquinolones and rhegmatogenous retinal detachment: a population-based cohort study
https://www.ncbi.nlm.nih.gov/pubmed/24170197
Bilateral uveitis associated with fluoroquinolone therapy
Concentrations of the des-F -F(6)-quinolone garenoxacin in plasma and joint cartilage of immature rats https://www.ncbi.nlm.nih.gov/pubmed/14661070
Fluoroquinolone-induced retinal degeneration in cats
https://www.ncbi.nlm.nih.gov/pubmed/12479325
https://avmajournals.avma.org/doi/abs/10.2460/javma.2002.221.1568?journalCode=javma
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Pro-apoptotic effect of new quinolone
https://www.sciencedirect.com/science/article/pii/S0887233316300285
https://www.ncbi.nlm.nih.gov/pubmed/26916084
Third and Fourth Generation Fluoroquinolone
https://www.ncbi.nlm.nih.gov/pubmed/24410307
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
Safety issues and drug—drug
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Retinal Detachment and Fluoroquinolones
https://jamanetwork.com/journals/jama/article-abstract/1217224?resultClick=1&redirect=true
Oral Fluoroquinolones and the Risk
https://jamanetwork.com/journals/jama/fullarticle/1148331
Ocular toxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/17760640
Evaluation of photodegradation, phototoxicity and photogenotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25728226
https://www.sciencedirect.com/science/article/pii/S101113441500041X
Evaluation of gatifloxacin for eye
https://www.ncbi.nlm.nih.gov/pubmed/25028261
http://journals.sagepub.com/doi/abs/10.1177/0960327114530743
Flashes, Floaters and Oral Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183446/pdf/nihms519503.pdf
Detection and Prevention of Ocular Phototoxicity of Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910230/pdf/nihms-204214.pdf
Cross-Reactivity in Murine Fluoroquinolone Photoallergy
http://www.jimmunol.org/content/jimmunol/160/8/3719.full.pdf
Binocular Diplopia: A Possible Adverse Effect of Fluoroquinolone Therapy
https://www.hindawi.com/journals/criopm/2020/8843182/
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells https://www.sciencedirect.com/science/article/pii/S0014483521004231
Impacts of Bacteriostatic and Bactericidal Antibiotics on the Mitochondria of the Age-Related Macular Degeneration Cybrid Cell Lines
https://pubmed.ncbi.nlm.nih.gov/35625603/
Oral Fluoroquinolones and the Risk of Retinal Detachment
https://www.academia.edu/20453194/Oral_Fluoroquinolones_and_the_Risk_of_Retinal_Detachment
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells
Ophthalmotoxicity and ototoxicity of the new quinolone antibacterial agent levofloxacin in Long Evans rats.
https://europepmc.org/article/med/1622440
Ototoxicity of Topical Moxifloxacin in a Chinchilla Animal Model
https://onlinelibrary.wiley.com/doi/abs/10.1097/MLG.0b013e318148b275
ONCOGENESIS
Ciprofloxacin decreases survival in HT-29 cells via
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707983/pdf/bph0157-0362.pdf
Type II topoisomerases—inhibitors, repair mechanisms and mutations
https://www.ncbi.nlm.nih.gov/pubmed/19762349
DNA ADDUCTION IN CONTEXT NATIVE METABOLIC
The photomutagenicity of fluoroquinolones in tests for gene mutation
Chromosomal Aberrations and Genomic Instability Induced by Topoisomerase-
OTIC (auditory)
Off-label use of otic ciprofloxacin/dexamethasone led to hyperglycemia in infant: Case report
Risk for Tympanic Membrane Perforation After Quinolone Ear Drops for Acute Otitis Externa
https://academic.oup.com/cid/article/70/6/1103/5482480
P450 AND OTHER METABOLIZATION
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Pharmacokinetic interactions related to the chemical structures of Fluoroquinolones
https://academic.oup.com/jac/article/37/suppl_A/41/816317
FLUOROQUINOLONE ANTIBIOTICS INHIBIT CYTOCHROME P450
https://www.ncbi.nlm.nih.gov/pubmed/8894516
Chronic administration of caderofloxacin,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820800/pdf/aps2015160a.pdf
Alteration of pharmacokinetics of cyclophosphamide and suppression of
https://www.nature.com/articles/1703815.pdf
Base-displaced intercalation of the2-amino-3-methylimidazo[4,5-f]quinoloneN2-dGadduct in theNarI DNA recognition sequence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950664/pdf/gkt1109.pdf
Fluoroquinolone toxicity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981197/pdf/cp-2012-4-e87.pdf
Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2
https://www.nature.com/articles/aps2008184.pdf
Pharmacokinetic Pharmacokinetic drug‑drug interaction and theirdrug drug
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897029/
Hepatocytes-the choice to investigate drug metabolism and toxicity in man
https://www.ncbi.nlm.nih.gov/pubmed/17134688
DNA ADDUCTION IN CONTEXT NATIVE METABOLIC
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
Safety issues and drug—drug interactions
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Mechanisms of trovafloxacin hepatotoxicity studies
https://www.sciencedirect.com/science/article/pii/S0960894X07012498
https://www.ncbi.nlm.nih.gov/pubmed/17976985
Effects of fluoroquinolones on CYP4501A and 3A in male broilers
https://pubmed.ncbi.nlm.nih.gov/20580800/
Inhibitory effect of several fluoroquinolones on hepatic microsomal Cytochrome P-450
https://www.ncbi.nlm.nih.gov/pubmed/16343288
The influence of a newly developed quinolone Antofloxacin
PANCREACTIC
Outpatient Gatifloxacin Therapy
Effect of fluoroquinolones on mitochondrial function in pancreatic beta cells
https://www.ncbi.nlm.nih.gov/pubmed/24284031
http://www.sciencedirect.com/science/article/pii/S0928098713004508?via%3Dihub
PEDIATRIC
Perceived Harm May Be Helpful: Fear of Fluoroquinolone-Associated Adverse Events in Children | American Academy of Pediatrics
https://pediatrics.aappublications.org/content/147/6/e2021050321
PHOTOTOXICITY
2015 Effect of norfloxacin and moxifloxacin on melanin synthesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315488/pdf/11010_2014_Article_2297.pdf
Alteration of the endocytotic pathway by photosensitization with fluoroquinolones
http://onlinelibrary.wiley.com/doi/10.1562/0031-8655(2000)0720458AOTEPB2.0.CO2/full
Clinical toxicological aspects of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/12052667
Combined Use of In Vitro Phototoxic Assessments and Cassette Dosing
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160149/pdf/12248_2011_Article_9292.pdf
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones
https://www.sciencedirect.com/science/article/abs/pii/S1011134400001019
DNA Damage from Phototoxicity of Quinolones
http://www.chinaphar.com/article/view/7857/8443
Evaluation of photodegradation, phototoxicity and photogenotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25728226
https://www.sciencedirect.com/science/article/pii/S101113441500041X
Inhibition of Human Topoisomerase II by Fluoroquinolones and Ultraviolet A Irradiation
https://academic.oup.com/toxsci/article/69/1/16/1707336
Formation of Antigenic Quinolone Photoadducts on Langerhans Cells Initiates
http://www.sciencedirect.com/science/article/pii/S0022202X15408115
https://www.ncbi.nlm.nih.gov/pubmed/10692119
Lysosomal Membrane Permeabilization Induces Cell Death
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/pdf/20021952.pdf
Ocular toxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/17760640
Oxidative Damage to RPA Limits the Nucleotide
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669849/pdf/emss-66122.pdf
Photodegradation assessment of ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750423/pdf/1752-153X-7-133.pdf
Photosensitization Reactions of Fluoroquinolones
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.00978.x/full
https://www.ncbi.nlm.nih.gov/pubmed/21770950
Phototoxicity in quinolones- comparison of ciprofloxacin and grepafloxacin
https://pubmed.ncbi.nlm.nih.gov/9484878/
Photosensitizing Mechanism and Identification of Levofloxacin Photoproducts
https://www.ncbi.nlm.nih.gov/pubmed/22211524
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.01068.x/abstract
Photosensitized DNA Damage The Case of Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/19320842
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2009.00548.x/abstract
Effect of new synthetically prepared quinolone
https://acs.fchpt.stuba.sk/?id=7&paper=58
Stimulation of Prostaglandin Production by Quinolone Phototoxicity in Balb/c 3T3 mouse fibroblast cells in vitro
https://pubmed.ncbi.nlm.nih.gov/9143485/
Synthesis and photo DNA-damaging activities
https://www.sciencedirect.com/science/article/pii/S0040403906013475
The photomutagenicity of fluoroquinolones and other
http://www.sciencedirect.com/science/article/pii/S0378427498002355
The photomutagenicity of fluoroquinolones in tests for gene
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
Pro-apoptotic effect of new quinolone
https://www.sciencedirect.com/science/article/pii/S0887233316300285
https://www.ncbi.nlm.nih.gov/pubmed/26916084
Quinolone antibacterials a new class of photochemical carcinogens
https://www.ncbi.nlm.nih.gov/pubmed/9085565
http://www.sciencedirect.com/science/article/pii/S1011134496074258?via%3Dihub
Safety of fluoroquinolones update
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094848/pdf/JID13054.pdf
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Photochemical mutagenicity of phototoxic and photochemically carcinogenic fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/11131036
https://link.springer.com/article/10.1007%2Fs002040000162?LI=true
In vitro phototoxicity of new quinolones
https://www.ncbi.nlm.nih.gov/pubmed/10599972
http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0781.1999.tb00094.x/abstract
Possible involvement of DEC1 on the adverse effects of quinolone antibiotics
http://www.myquinstory.info/wp-content/uploads/2010/01/Shi-2010-DEC1.pdf
PREGNANCY
Pregnancy Outcome Following Gestational Exposure
https://journals.asm.org/doi/10.1128/aac.42.6.1336
Safety study of Ciprofloxacin in newborn mice
https://www.ncbi.nlm.nih.gov/pubmed/26627140
https://www.sciencedirect.com/science/article/pii/S0273230015301173
Further analysis of the risk of adverse birth outcome after
https://www.ncbi.nlm.nih.gov/pubmed/16144758
Embryotoxic and Teratogenic Effects of Norfloxacin in Pregnant Female Albino Rats
https://www.hindawi.com/journals/aps/2014/924706/
Effects of Fluoroquinolones and magnesium deficiency
https://link.springer.com/article/10.1007/s002040050521
Teratogenic Effects Minimization of Norfloxacin in Pregnant and Breast feeding Female https://www.academia.edu/10794897/Teratogenic_Effects_Minimization_of_Norfloxacin_in_Pregnant_and_Breast_feeding_Female
PSYCHIATRIC
Fluoroquinolone –Induced Suicidal Ideation and Suicidality
http://www.psychosomaticsjournal.com/article/S0033-3182(11)00213-1/fulltext
Levaquin induced acute psychosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/
Neuropsychological Side Effects Associated with Fluoroquinolone Therapy: A Qualitative Review with Recommendations for Future Research
https://www.medicalandresearch.com/assets/articles/documents/DOCUMENT_20220203153039.pdf
Quinolones-Induced Musculoskeletal, Neurological, and Psychiatric ADRs: A Pharmacovigilance Study Based on Data From the Italian Spontaneous Reporting System
PULMONARY
Acute and subacute (20-d) oral dose toxicity study of modified fluoroquinolone compound 6C in BALB/c
http://www.tandfonline.com/doi/abs/10.3109/15569543.2015.1076483?src=recsys&journalCode=itxr20
Quinolone-Induced Upregulation of Osteopontin Gene Promoter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370769/pdf/zac2868.pdf
Floxacin Antibiotics May Augment Treatment of Lung RSK4
RENAL
Acute and subacute (20-d) oral dose toxicity study of modified fluoroquinolone compound 6C in BALB/c
http://www.tandfonline.com/doi/abs/10.3109/15569543.2015.1076483?src=recsys&journalCode=itxr20
Adverse Drug Reactions Related to the use of
Adverse Effects
http://www.asmscience.org/content/book/10.1128/9781555817817.chap25
Fluoroquinolone-Induced Renal Failure
https://pubmed.ncbi.nlm.nih.gov/10877041/
Melatonin can attenuate ciprofloxacin induced nephrotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/27780148
Risk of acute kidney injury associated with the use
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708027/pdf/185e475.pdf
Crystal-induced acute kidney injury due to ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316583/pdf/JNP-4-29.pdf
Fluoroquinolones-Induced Tendinitis and Tendon
https://www.ncbi.nlm.nih.gov/pubmed/17580216
Nanobiotics Effects of Fluoroquinolones in Mammalian Cells
https://pmc.ncbi.nlm.nih.gov/articles/PMC4571980/
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action
https://www.ncbi.nlm.nih.gov/pubmed/18706903
http://www.sciencedirect.com/science/article/pii/S0014299908008054?via%3Dihub
Safety issues and drug—drug interactions
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells
https://pdfs.semanticscholar.org/0eef/309042885bf1fe3befcf0b5ccb7540840342.pdf
Non-antibiotic-effects-of-fluoroquinolones-in-mammalian-cells
http://www.jbc.org/content/290/36/22287.full.pdf
Levofloxacin-induced crystal nephropathy
http://onlinelibrary.wiley.com/doi/10.1111/nep.12405/abstract
https://www.ncbi.nlm.nih.gov/pubmed/25900386
Fluoroquinolone-induced acute interstitial nephritis
https://academic.oup.com/ndt/article/21/1/237/1819025
DETERMINATION OF THE EFFECTS OF CIPROFLOXACIN
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794863
Levofloxacin-induced rhabdomyolysis: a case report
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-1004-6
REPRODUCTIVE
Antibiotics effect on testis tissue in rats
Assessment on the adverse effects of Aminoglycosides and Flouroquinolone on sperm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426151/pdf/ijrm-3-125.pdf
Boar spermatozoa successfully predict mitochondrial modes of toxicity
https://www.ncbi.nlm.nih.gov/pubmed/25624015
Reproduction Toxicology
The effect of ciprofloxacin on sperm DNA damage, fertility potential and early
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312808/pdf/vrf-3-131.pdf
Evaluation of ameliorative potential of supranutritional selenium on
https://www.ncbi.nlm.nih.gov/pubmed/27083143
Role of Mitochondria in Ciprofloxacin Sperm Cells
https://pubmed.ncbi.nlm.nih.gov/23420823/
Long-Term Effect of Ciprofloxacin on Testicular Tissue: Evidence for Biochemical and Histochemical Changes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850316/
RESIDUES
Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity
RESISTANCE
Covalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166900/pdf/fchem-02-00071.pdf
Reduction of hospital levofloxacin use is associated with a decrease in hospital-acquired fluoroquinolone-resistant Pseudomonas aeruginosa rates: An 11 year study
http://www.e-jmii.com/article/S1684-1182(15)00481-8/pdf
http://www.e-jmii.com/article/S1684-1182(15)00481-8/abstract
Quinolones: A Comprehensive Review
https://www.aafp.org/afp/2002/0201/p455.pdf
Concerns about extralabel fluoroquinolone use in food-producing animals
https://avmajournals.avma.org/doi/pdf/10.2460/javma.243.9.1242
Type II topoisomerase mutations in Bacillus anthracis
https://academic.oup.com/jac/article/54/1/90/746841
https://www.ncbi.nlm.nih.gov/pubmed/15190035
The Fluoroquinolones: How Long Will Their Utility Last?
https://www.ncbi.nlm.nih.gov/pubmed/15061660
http://www.tandfonline.com/doi/abs/10.1080/00365540410019039?journalCode=infd19
Association between fluoroquinolone resistance and MRSA genotype in Alexandria, Egypt
SAR
Investigating the fluoroquinolone-topoisomerase interaction by use of novel fluoroquinolone and quinazoline analogs use of novel fluoroquinolone and quinazoline analogs
SERUM SICKNESS
Serum Sickness-Like Illness Associated with Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC171716/pdf/aac00061-0258.pdf
SPECTROMETRY AND RELATED
7-{4-[(1,3-Benzodioxol-5-yl) methyl]-piperazin-1-yl}-1-cyclopropyl-6-fluoro-4-c
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394047/pdf/e-68-o2264.pdf
A Convergent Synthetic Route to (+)-Dynemicin A and Analogs of Wide Structural Variability
http://pubs.acs.org/doi/abs/10.1021/ja9703741
A Mild and Efficient Synthesis of 4-Quinolones and Quinolone Heterocycles
https://www.ncbi.nlm.nih.gov/pubmed/17458997
http://pubs.acs.org/doi/pdf/10.1021/jo070181o
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf
Acyl Glucuronide DNA-adducts from Quinolones
https://pdfs.semanticscholar.org/78ee/bbe021406be4a6a23af1de4b16323f765fb5.pdf
Analysis of positions and substituents on genotoxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/27835744
A THEORETICAL-EXPERIMENTAL STUDY ON THE STRUCTURE AND ACTIVITY OF
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365236/pdf/MBD-07-301.pdf
Analytical profile of the fluoroquinolone antibacterials
https://www.ajol.info/index.php/ajb/article/view/58495/46839
A New Silver Complex with Ofloxacin
https://www.degruyter.com/downloadpdf/j/amma.2015.62.issue-2/amma-2015-0091/amma-2015-0091.pdf
An Adduct of Magnesium Sulfate with ciprofloxacin
http://scripts.iucr.org/cgi-bin/paper?S0108270196005343
Analytical methods for determination of new fluoroquinolones in biological matrices
https://link.springer.com/article/10.1007/s00216-011-5706-8
Analysis of the factors that significantly influence the stability of
https://www.ncbi.nlm.nih.gov/pubmed/19576385
Chemistry of 4-Hydroxy-2(1H)-quinolone. Part 1 - Synthesis and reactions
http://www.sciencedirect.com/science/article/pii/S187853521400015X
Biological activities of some Fluoroquinolones-metal complexes
HIGH-RESOLUTION MASS SPECTROMETRY APPLIED TO THE IDENTIFICATION OF TRANSFORMATION PRODUCTS OF QUINOLONES
http://diposit.ub.edu/dspace/bitstream/2445/50423/1/633709.pdf
DNA interaction, in vitro antimicrobial and SOD-like activity of copper
https://www.sciencedirect.com/science/article/pii/S0022328X11007388
Chapter- 7
http://shodhganga.inflibnet.ac.in/bitstream/10603/11316/10/chapter-%207.pdf
Characterization of intermediate compounds formed
http://onlinelibrary.wiley.com/doi/10.1002/rcm.3537/abstract
Validation of a liquid chromatography–tandem mass spectrometric method
https://www.sciencedirect.com/science/article/pii/S0003267004008529
Tandem mass spectrometric study of ciprofloxacin–poly(ethylene glycol)
https://www.sciencedirect.com/science/article/pii/S1387380608002108
Copper(II) complexes with norfloxacin and neutral terpyridines Cytotoxic,
https://www.sciencedirect.com/science/article/pii/S0277538712002112
Evaluation and degradation Chemistry of Orbifloxacin using LC-MS
https://www.ijsciences.com/pub/article/257
Ciprofloxacin induced neurotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25902267
Ciprofloxacin is an inhibitor of the Mcm2-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/pdf/bsr033e072.pdf
Investigating the fluoroquinolone-topoisomerase interaction by use of
http://ir.uiowa.edu/cgi/viewcontent.cgi?article=2403&context=etd
Synthesis and Pharmacological Activity of Enoxacin Metal Complexes
http://www.journalijar.com/uploads/2013-11-01_110511_541.pdf
Confirmation of fluoroquinolone residues in salmon
Synthesis, characterization, antimicrobial and cytotoxicity
https://www.sciencedirect.com/science/article/abs/pii/S0162013406001735
Spectroscopic Studies on the Binding of
https://pdfs.semanticscholar.org/6bfa/b49fd50684b13a85f0b6c7668987a8ad7d55.pdf
A comparative analysis of chromosomal aberrations in cultured human lymphocytes
https://link.springer.com/article/10.1007/s00204-009-0509-9
https://www.ncbi.nlm.nih.gov/pubmed/20049419
Evaluation of the levofloxacin release characters
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260945/pdf/ijn-7-001.pdf
Development and validation of LC ESI MS MS method for analysis of moxifloxacin and
https://www.ncbi.nlm.nih.gov/pubmed/26730550
Liquid chromatography-electrospray ionization-mass spectrometry
https://www.ncbi.nlm.nih.gov/pubmed/16272169
Synthesis, characterization and DNA binding of magnesium-ciprofloxacin
http://www.bf.uni-lj.si/fileadmin/groups/2747/Zaposleni/Natasa_Poklar_Ulrih/2006-NPU-JIB.pdf
Determination of Enantiomeric Impurity in Besifloxacin
http://onlinelibrary.wiley.com/doi/10.1002/chir.22042/abstract
Simultaneous Determination of the Residues of Fourteen
https://cjfs.agriculturejournals.cz/pdfs/cjf/2012/01/10.pdf
Rapid, sensitive and selective HPLC-MS/MS method for the quantification of topically applied besifloxacin in rabbit plasma and ocular tissues: Application to a pharmacokinetic study
https://pubmed.ncbi.nlm.nih.gov/26340560/
Electrochemical oxidation of fluoroquinolone antibiotics Mechanism
Photodegradation assessment of ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750423/pdf/1752-153X-7-133.pdf
Liquid chromatography–tandem mass spectrometry
ANTIBIOTICS IN PLASMA by LCMS
https://www.eurekakit.com/wp-content/uploads/2020/09/LC79210_ANTIBIOTICS_001.pdf
Mass spectrometic study of speciation in aluminium fluoroquinolone solutions
https://www.ncbi.nlm.nih.gov/pubmed/22837440
http://journals.sagepub.com/doi/abs/10.1255/ejms.1183?journalCode=emsa
The Effect of Some Fluoroquinolone Family Members
https://pdfs.semanticscholar.org/2439/2c5c31fdfcf55478b7c6e62234e1fed0560b.pdf
KINETIC AND THERMODYNAMIC STUDIES OF MOXIFLOXACIN
http://www.ptfarm.pl/pub/File/Acta_Poloniae/2012/5/821.pdf
Evaluation and Degradation Chemistry of Orbifloxacin Using LC-MS
https://www.ijsciences.com/pub/article/257
FQ and Metabolites in Chicken Muscles using MS-MS Barcelona Spain
http://diposit.ub.edu/dspace/bitstream/2445/50423/1/633709.pdf
FDA FQ residue
Defluorinated Sparfloxacin as a New Photoproduct Identified
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105763/pdf/ac001151.pdf
STATISTICS
An Update on Fluoroquinolones: The Emergence of a Multisystem Toxicity Syndrome
TENDON RUPTURE
DIAGNOSTIC FAILURE OF CIPROFLOXACIN-INDUCED SPONTANEOUS
https://www.ncbi.nlm.nih.gov/pubmed/21658328
Fluoroquinolones-Induced Tendinitis and Tendon Rupture in Kidney Transplant Recipients: 2 Cases and a Review of the Literature
Quinolone Ear Drops and Achilles Tendon Rupture
Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study
THEORECTICAL MODELING
2D, 3D-QSAR and molecular
THYROID
Ciprofloxacin induced hormonal changes in the thyroid gland of
http://iosrjournals.org/iosr-jpbs/papers/Vol5-issue3/C0531218.pdf?id=4840
Determination of zabofloxacin in rat plasma by liquid chromatography with
WHAT IS A DNA ADDUCT
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618519/pdf/ijms-18-01870.pdf
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057941/pdf/nihms559280.pdf
- https://www.ncbi.nlm.nih.gov/pubmed/17574899
- https://search.proquest.com/openview/89f86c786c8827ae7045ce7b88e62f26/1?pq-origsite=gscholar&cbl=18750&diss=y
- https://dge.carnegiescience.edu/SCOPE/SCOPE_52/SCOPE_52_2.01_Beland_29-56.pdf
- http://journals.sagepub.com/doi/pdf/10.1177/019262330002800308
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950664/pdf/gkt1109.pdf
- https://www.hindawi.com/journals/jna/2010/929047/ref/
- https://www.sciencedirect.com/topics/neuroscience/dna-adduct
- http://pubs.rsc.org/en/content/articlelanding/2015/cs/c5cs00316d#!divAbstract
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