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This library features a global collection of scientific publications, highlighting research related to fluoroquinolones, quinolones, and DNA. Entries are organized alphabetically by category for easy navigation.
NEPHROPATHY
Allergic Nephropathy Associated with Norfloxacin and Ciprofloxacin
https://www.tandfonline.com/doi/abs/10.3109/00365599709030647?journalCode=isju19
NEURAL
Fluorinated 4-quinolones induce hyperproduction of interleukin 2
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC287008/pdf/pnas00248-0298.pdf
Adverse Drug Reactions Related to the
Ciprofloxacin induced neurotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25902267
Effect of ciprofloxacin and levofloxacin on some oxidative stress parameters in brain regions
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.893.9513&rep=rep1&type=pdf
Fluoroquinolone-related neuropsychiatric
https://www.ncbi.nlm.nih.gov/pubmed/26955658
Determination of the Excitatory Potencies of Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105691/pdf/ac001831.pdf
Effects of Novel 6-Desfluoroquinolones and Classic Quinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC89352/pdf/ac001729.pdf
Effects of sparfloxacin on CNS functions
https://www.ncbi.nlm.nih.gov/pubmed/16701999
Fluoroquinolones induced suicidal ideation
http://www.sciencedirect.com/science/article/pii/S0163834309000486?via%3Dihub
Possible Intermolecular Interaction between Quinolones and Biphenylacetic Acid Inhibit sy-Amino butyric Acid Receptor Sites
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC284738/pdf/aac00374-0093.pdf
Levofloxacin-induced Myasthenic Crisis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564188/pdf/662.pdf
Gemifloxacin-Associated Neurotoxicity Presenting
Permanent Peripheral Neuropathy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528905/pdf/10.1177_2324709614545225.pdf
Levofloxacin-associated hypoglycaemia complicated by pontine myelinolysis and quadriplegia
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613252/pdf/dme0025-0856.pdf
Levofloxacin-induced myasthenic crisis
http://www.jem-journal.com/article/S0736-4679(12)01199-7/abstract
https://www.ncbi.nlm.nih.gov/pubmed/23218195
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564188/pdf/662.pdf
Exploration of neurotoxicity of ciprofloxacin
http://www.academicjournals.org/article/article1423846203_Arafa%20et%20al.pdf
Peripheral Neuropathy Associated with Fluoroquinolones
https://pubmed.ncbi.nlm.nih.gov/1352007/
Peripheral sensory disturbances related to treatment with Fluoroquinolones
Possible interaction of fluoroquinolones with GABA
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368276/pdf/brjclinpharm00069-0066.pdf
Quinolone antibiotics and suicidal behavior analysis
https://www.ncbi.nlm.nih.gov/pubmed/27113226
Potential Interactions CNS
https://link.springer.com/article/10.2165/00002018-199921020-00005
Quinolones review of psychiatric and neurological adverse reactions
Unexpected, severe central nerve system toxicity of
https://www.ncbi.nlm.nih.gov/pubmed/17268904
Safety issues and drug—drug
https://www.ncbi.nlm.nih.gov/pubmed/25423877
The neuroprotective role of Nigella sativa extract on
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
The Role of Mitochondria in Brain Aging and the Effects of Melatonin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001212/pdf/CN-8-182.pdf
Third and Fourth Generation Fluoroquinolone
https://www.ncbi.nlm.nih.gov/pubmed/24410307
Antibiotic-Induced Neurotoxicity
Convulsant and Subconvulsant Doses of Norfloxacin in the Presence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC127025/pdf/0301.pdf
Enhanced susceptibility of pentylenetetrazole kindled mice to quinolone effects
https://www.sciencedirect.com/science/article/abs/pii/S0924857999000679
Evaluation of the Possible Epileptogenic Activity of Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pubmed/23086472
Fluoroquinolone treatment alters the peptidergic innervation of rat salivary
http://onlinelibrary.wiley.com/doi/10.1002/ar.21037/full
Hippocampal Activity in the Presence of Quinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC284301/pdf/aac00376-0152.pdf
In Vitro Modulation of Hippocampal Pyramidal Cell Response
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC163578/pdf/402573.pdf
Effect of fluoroquinolones for Anticonvulsant activities on PTZ induced seizures
http://www.journalijar.com/uploads/2013-11-01_111226_981.pdf
Fluoroquinolone toxicity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981197/pdf/cp-2012-4-e87.pdf
Hereditary Neuropathy Unmasked by Levofloxacin
https://fqresearch.org/pdf_files/hereditary-neuropathy-unmasked-by-levaquin.pdf
A pharmacokinetic/pharmacodynamic approach to show that not all fluoroquinolones exhibit similar sensitivity toward the proconvulsant effect of biphenyl acetic acid in rats
https://academic.oup.com/jac/article/48/6/813/743793
Adverse Reactions to Fluoroquinolones. An Overview on Mechanistic Aspects
Treatment of the Fluoroquinolone Associated Disability –
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632915/pdf/OMCL2017-8023935.pdf
https://www.hindawi.com/journals/omcl/2017/8023935/
Effect of Bile Duct Ligation and Unilateral Nephrectomy on Brain Concentration and Convulsant Potential of the Quinolone
https://academic.oup.com/toxsci/article/29/2/280/1623527
Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots
http://www.sciencedirect.com/science/article/pii/S0301008215300605?via%3Dihub
https://www.ncbi.nlm.nih.gov/pubmed/26603930?dopt=AbstractPlus
Neuropsychiatric reactions to drugs an analysis of spontaneous
https://www.ncbi.nlm.nih.gov/pubmed/15661570
Oral fluoroquinolones and risk of secondary pseudotumor cerebri syndrome
http://n.neurology.org/content/early/2017/07/28/WNL.0000000000004247.short
Peripheral neuropathy and Guillain-Barré
https://www.ncbi.nlm.nih.gov/pubmed/24472364
https://www.sciencedirect.com/science/article/pii/S1047279713004754
Proteins from Human Cerebrospinal Fluid
http://science.sciencemag.org/content/182/4109/296
Effect of Ciprofloxacin Injection on Genetically Absence Prone (Wag/Rij) Rat's Electroencephalogram Characteristics
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202555/pdf/BCN-4-031.pdf
The effect of levofloxacin and moxifloxacin on cardiovascular
https://www.ncbi.nlm.nih.gov/pubmed/22621918
Association of a Tourette-like Syndrome with Sparfloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034196/pdf/main.pdf
Levaquin induced acute psychosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/?report=printable
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/
Safety of fluoroquinolones update
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094848/pdf/JID13054.pdf
Reversible craniocervical dystonia associated with
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710986/pdf/40734_2015_Article_21.pdf
Ch 16 - The Quinolones: Prospects
https://www.sciencedirect.com/science/article/pii/B9780120595174500179
Anxiogenic and proconvulsant effect of gatifloxacin in mice
https://www.ncbi.nlm.nih.gov/pubmed/18022617
http://www.sciencedirect.com/science/article/pii/S001429990701196X
Generalized Seizure and Toxic Epidermal Necrolysis Following
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Fluoroquinolone –Induced Suicidal Ideation and Suicidality
http://www.psychosomaticsjournal.com/article/S0033-3182(11)00213-1/fulltext
Possible involvement of DEC1 on the adverse effects of quinolone antibiotics
http://www.myquinstory.info/wp-content/uploads/2010/01/Shi-2010-DEC1.pdf
https://www.ncbi.nlm.nih.gov/pubmed/2021494
Neuropsychological Side Effects Associated with Fluoroquinolone Therapy: A Qualitative Review with Recommendations for Future Research
https://www.medicalandresearch.com/assets/articles/documents/DOCUMENT_20220203153039.pdf
A VigiBase Descriptive Study of Fluoroquinolone-Associated Peripheral Nervous System Disorders https://mdpi-res.com/d_attachment/pharmaceuticals/pharmaceuticals-15-00143/article_deploy/pharmaceuticals-15-00143.pdf
NM NUCLEAR MEDICINE
Analytical methods for determination of new fluoroquinolones in biological matrices
https://link.springer.com/article/10.1007/s00216-011-5706-8
Ciprofloxacin is an inhibitor of the Mcm2-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/pdf/bsr033e072.pdf
Synthesis, characterization, antimicrobial
https://link.springer.com/article/10.1007/s00706-015-1507-7
A comparative analysis of chromosomal aberrations in cultured human lymphocytes https://link.springer.com/article/10.1007/s00204-009-0509-9
Fluoroquinolone-Associated Movement Disorder: A Literature Review
OCULAR
Phototoxic Lesions Induced by Quinolone
https://www.ncbi.nlm.nih.gov/pubmed/8052802
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells
https://www.sciencedirect.com/science/article/pii/S0014483521004231
2015 Effect of norfloxacin and moxifloxacin on melanin synthesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315488/pdf/11010_2014_Article_2297.pdf
Adverse Effects of Antimicrobials via Predictable or Idiosyncratic effects
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421593/pdf/zac4046.pdf
Association Between Recent Use of fluoroquinolones and rhegmatogenous retinal detachment: a population-based cohort study
https://www.ncbi.nlm.nih.gov/pubmed/24170197
Bilateral uveitis associated with fluoroquinolone therapy
Concentrations of the des-F -F(6)-quinolone garenoxacin in plasma and joint cartilage of immature rats https://www.ncbi.nlm.nih.gov/pubmed/14661070
Fluoroquinolone-induced retinal degeneration in cats
https://www.ncbi.nlm.nih.gov/pubmed/12479325
https://avmajournals.avma.org/doi/abs/10.2460/javma.2002.221.1568?journalCode=javma
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Pro-apoptotic effect of new quinolone
https://www.sciencedirect.com/science/article/pii/S0887233316300285
https://www.ncbi.nlm.nih.gov/pubmed/26916084
Third and Fourth Generation Fluoroquinolone
https://www.ncbi.nlm.nih.gov/pubmed/24410307
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
Safety issues and drug—drug
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Retinal Detachment and Fluoroquinolones
https://jamanetwork.com/journals/jama/article-abstract/1217224?resultClick=1&redirect=true
Oral Fluoroquinolones and the Risk
https://jamanetwork.com/journals/jama/fullarticle/1148331
Ocular toxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/17760640
Evaluation of photodegradation, phototoxicity and photogenotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25728226
https://www.sciencedirect.com/science/article/pii/S101113441500041X
Evaluation of gatifloxacin for eye
https://www.ncbi.nlm.nih.gov/pubmed/25028261
http://journals.sagepub.com/doi/abs/10.1177/0960327114530743
Flashes, Floaters and Oral Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183446/pdf/nihms519503.pdf
Detection and Prevention of Ocular Phototoxicity of Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910230/pdf/nihms-204214.pdf
Cross-Reactivity in Murine Fluoroquinolone Photoallergy
http://www.jimmunol.org/content/jimmunol/160/8/3719.full.pdf
Binocular Diplopia: A Possible Adverse Effect of Fluoroquinolone Therapy
https://www.hindawi.com/journals/criopm/2020/8843182/
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells https://www.sciencedirect.com/science/article/pii/S0014483521004231
Impacts of Bacteriostatic and Bactericidal Antibiotics on the Mitochondria of the Age-Related Macular Degeneration Cybrid Cell Lines
https://pubmed.ncbi.nlm.nih.gov/35625603/
Oral Fluoroquinolones and the Risk of Retinal Detachment
https://www.academia.edu/20453194/Oral_Fluoroquinolones_and_the_Risk_of_Retinal_Detachment
Effects of fluoroquinolones and tetracyclines on mitochondria of human retinal MIO-M1 cells
Ophthalmotoxicity and ototoxicity of the new quinolone antibacterial agent levofloxacin in Long Evans rats.
https://europepmc.org/article/med/1622440
Ototoxicity of Topical Moxifloxacin in a Chinchilla Animal Model
https://onlinelibrary.wiley.com/doi/abs/10.1097/MLG.0b013e318148b275
ONCOGENESIS
Ciprofloxacin decreases survival in HT-29 cells via
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707983/pdf/bph0157-0362.pdf
Type II topoisomerases—inhibitors, repair mechanisms and mutations
https://www.ncbi.nlm.nih.gov/pubmed/19762349
DNA Adducts - mutations – cancer
http://aether.cmi.ua.ac.be/artikels/MB_30229.pdf
DNA ADDUCTION IN CONTEXT NATIVE METABOLIC
The photomutagenicity of fluoroquinolones in tests for gene mutation
Chromosomal Aberrations and Genomic Instability Induced by Topoisomerase-
OTIC (auditory)
Off-label use of otic ciprofloxacin/dexamethasone led to hyperglycemia in infant: Case report
Risk for Tympanic Membrane Perforation After Quinolone Ear Drops for Acute Otitis Externa
https://academic.oup.com/cid/article/70/6/1103/5482480
P450 AND OTHER METABOLIZATION
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Pharmacokinetic interactions related to the chemical structures of Fluoroquinolones
https://academic.oup.com/jac/article/37/suppl_A/41/816317
FLUOROQUINOLONE ANTIBIOTICS INHIBIT CYTOCHROME P450
https://www.ncbi.nlm.nih.gov/pubmed/8894516
Chronic administration of caderofloxacin,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820800/pdf/aps2015160a.pdf
Alteration of pharmacokinetics of cyclophosphamide and suppression of
https://www.nature.com/articles/1703815.pdf
Base-displaced intercalation of the2-amino-3-methylimidazo[4,5-f]quinoloneN2-dGadduct in theNarI DNA recognition sequence
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950664/pdf/gkt1109.pdf
Fluoroquinolone toxicity
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3981197/pdf/cp-2012-4-e87.pdf
Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2
https://www.nature.com/articles/aps2008184.pdf
Pharmacokinetic Pharmacokinetic drug‑drug interaction and theirdrug drug
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897029/
Hepatocytes-the choice to investigate drug metabolism and toxicity in man
https://www.ncbi.nlm.nih.gov/pubmed/17134688
DNA ADDUCTION IN CONTEXT NATIVE METABOLIC
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
Safety issues and drug—drug interactions
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Mechanisms of trovafloxacin hepatotoxicity studies
https://www.sciencedirect.com/science/article/pii/S0960894X07012498
https://www.ncbi.nlm.nih.gov/pubmed/17976985
Effects of fluoroquinolones on CYP4501A and 3A in male broilers
http://beyotime.net/reference/p0018-ref47.pdf
Inhibitory effect of several fluoroquinolones on hepatic microsomal Cytochrome P-450
https://www.ncbi.nlm.nih.gov/pubmed/16343288
The influence of a newly developed quinolone Antofloxacin
PANCREACTIC
Outpatient Gatifloxacin Therapy
Effect of fluoroquinolones on mitochondrial function in pancreatic beta cells
https://www.ncbi.nlm.nih.gov/pubmed/24284031
http://www.sciencedirect.com/science/article/pii/S0928098713004508?via%3Dihub
PEDIATRIC
Perceived Harm May Be Helpful: Fear of Fluoroquinolone-Associated Adverse Events in Children | American Academy of Pediatrics
https://pediatrics.aappublications.org/content/147/6/e2021050321
PHOTOTOXICITY
2015 Effect of norfloxacin and moxifloxacin on melanin synthesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315488/pdf/11010_2014_Article_2297.pdf
Alteration of the endocytotic pathway by photosensitization with fluoroquinolones
http://onlinelibrary.wiley.com/doi/10.1562/0031-8655(2000)0720458AOTEPB2.0.CO2/full
Clinical toxicological aspects of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/12052667
Combined Use of In Vitro Phototoxic Assessments and Cassette Dosing
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160149/pdf/12248_2011_Article_9292.pdf
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones
https://www.sciencedirect.com/science/article/pii/S1011134400001019
DNA Damage from Phototoxicity of Quinolones
http://www.chinaphar.com/article/view/7857/8443
Evaluation of photodegradation, phototoxicity and photogenotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25728226
https://www.sciencedirect.com/science/article/pii/S101113441500041X
Inhibition of Human Topoisomerase II by Fluoroquinolones and Ultraviolet A Irradiation
https://academic.oup.com/toxsci/article/69/1/16/1707336
Formation of Antigenic Quinolone Photoadducts on Langerhans Cells Initiates
http://www.sciencedirect.com/science/article/pii/S0022202X15408115
https://www.ncbi.nlm.nih.gov/pubmed/10692119
Lysosomal Membrane Permeabilization Induces Cell Death
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193790/pdf/20021952.pdf
Ocular toxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/17760640
Oxidative Damage to RPA Limits the Nucleotide
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669849/pdf/emss-66122.pdf
Photodegradation assessment of ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750423/pdf/1752-153X-7-133.pdf
Photosensitization Reactions of Fluoroquinolones
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.00978.x/full
https://www.ncbi.nlm.nih.gov/pubmed/21770950
Phototoxicity in quinolones- comparison of ciprofloxacin and grepafloxacin
https://pubmed.ncbi.nlm.nih.gov/9484878/
Photosensitizing Mechanism and Identification of Levofloxacin Photoproducts
https://www.ncbi.nlm.nih.gov/pubmed/22211524
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2011.01068.x/abstract
Photosensitized DNA Damage The Case of Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/19320842
http://onlinelibrary.wiley.com/doi/10.1111/j.1751-1097.2009.00548.x/abstract
Effect of new synthetically prepared quinolone
http://www.acs.chtf.stuba.sk/papers/acs_0058.pdf
Stimulation of Prostaglandin Production by Quinolone Phototoxicity in Balb/c 3T3 mouse fibroblast cells in vitro
https://pubmed.ncbi.nlm.nih.gov/9143485/
Synthesis and photo DNA-damaging activities
https://www.sciencedirect.com/science/article/pii/S0040403906013475
The photomutagenicity of fluoroquinolones and other
http://www.sciencedirect.com/science/article/pii/S0378427498002355
The photomutagenicity of fluoroquinolones in tests for gene
The Safety Profile of the Fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/10945507
Pro-apoptotic effect of new quinolone
https://www.sciencedirect.com/science/article/pii/S0887233316300285
https://www.ncbi.nlm.nih.gov/pubmed/26916084
Quinolone antibacterials a new class of photochemical carcinogens
https://www.ncbi.nlm.nih.gov/pubmed/9085565
http://www.sciencedirect.com/science/article/pii/S1011134496074258?via%3Dihub
Safety of fluoroquinolones update
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094848/pdf/JID13054.pdf
Fluoroquinolone Adverse Effects and Drug Interactions
http://onlinelibrary.wiley.com/doi/10.1592/phco.21.16.253S.33993/full
https://www.ncbi.nlm.nih.gov/pubmed/11642691
Photochemical mutagenicity of phototoxic and photochemically carcinogenic fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/11131036
https://link.springer.com/article/10.1007%2Fs002040000162?LI=true
In vitro phototoxicity of new quinolones
https://www.ncbi.nlm.nih.gov/pubmed/10599972
http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0781.1999.tb00094.x/abstract
Possible involvement of DEC1 on the adverse effects of quinolone antibiotics
http://www.myquinstory.info/wp-content/uploads/2010/01/Shi-2010-DEC1.pdf
PREGNANCY
Adverse Effects
http://www.asmscience.org/content/book/10.1128/9781555817817.chap25
Safety study of Ciprofloxacin in newborn mice
https://www.ncbi.nlm.nih.gov/pubmed/26627140
https://www.sciencedirect.com/science/article/pii/S0273230015301173
Further analysis of the risk of adverse birth outcome after
https://www.ncbi.nlm.nih.gov/pubmed/16144758
Embryotoxic and Teratogenic Effects of Norfloxacin in Pregnant Female Albino Rats
https://www.hindawi.com/journals/aps/2014/924706/
Effects of Fluoroquinolones and magnesium deficiency
https://link.springer.com/article/10.1007/s002040050521
Teratogenic Effects Minimization of Norfloxacin in Pregnant and Breast feeding Female https://www.academia.edu/10794897/Teratogenic_Effects_Minimization_of_Norfloxacin_in_Pregnant_and_Breast_feeding_Female
PSYCHIATRIC
Fluoroquinolone –Induced Suicidal Ideation and Suicidality
http://www.psychosomaticsjournal.com/article/S0033-3182(11)00213-1/fulltext
Levaquin induced acute psychosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745871/
Neuropsychological Side Effects Associated with Fluoroquinolone Therapy: A Qualitative Review with Recommendations for Future Research
https://www.medicalandresearch.com/assets/articles/documents/DOCUMENT_20220203153039.pdf
Quinolones-Induced Musculoskeletal, Neurological, and Psychiatric ADRs: A Pharmacovigilance Study Based on Data From the Italian Spontaneous Reporting System
PULMONARY
Acute and subacute (20-d) oral dose toxicity study of modified fluoroquinolone compound 6C in BALB/c
http://www.tandfonline.com/doi/abs/10.3109/15569543.2015.1076483?src=recsys&journalCode=itxr20
Quinolone-Induced Upregulation of Osteopontin Gene Promoter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370769/pdf/zac2868.pdf
Floxacin Antibiotics May Augment Treatment of Lung RSK4
RENAL
Acute and subacute (20-d) oral dose toxicity study of modified fluoroquinolone compound 6C in BALB/c
http://www.tandfonline.com/doi/abs/10.3109/15569543.2015.1076483?src=recsys&journalCode=itxr20
Adverse Drug Reactions Related to the use of
Adverse Effects
http://www.asmscience.org/content/book/10.1128/9781555817817.chap25
Fluoroquinolone-Induced Renal Failure
https://www.ncbi.nlm.nih.gov/pubmed/10877041
Melatonin can attenuate ciprofloxacin induced nephrotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/27780148
Risk of acute kidney injury associated with the use
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708027/pdf/185e475.pdf
Crystal-induced acute kidney injury due to ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316583/pdf/JNP-4-29.pdf
Fluoroquinolones-Induced Tendinitis and Tendon
https://www.ncbi.nlm.nih.gov/pubmed/17580216
Nanobiotics Effects of Fluoroquinolones in Mammalian Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf
http://www.jbc.org/content/290/36/22287.full.pdf
The perils of prescribing fluoroquinolones
https://ocimc.files.wordpress.com/2013/04/fluoroquinolones.pdf
The inhibition of gluconeogenesis by gatifloxacin may contribute to its hypoglycaemic action
https://www.ncbi.nlm.nih.gov/pubmed/18706903
http://www.sciencedirect.com/science/article/pii/S0014299908008054?via%3Dihub
Safety issues and drug—drug interactions
https://www.ncbi.nlm.nih.gov/pubmed/25423877
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells
https://pdfs.semanticscholar.org/0eef/309042885bf1fe3befcf0b5ccb7540840342.pdf
Non-antibiotic-effects-of-fluoroquinolones-in-mammalian-cells
http://www.jbc.org/content/290/36/22287.full.pdf
Levofloxacin-induced crystal nephropathy
http://onlinelibrary.wiley.com/doi/10.1111/nep.12405/abstract
https://www.ncbi.nlm.nih.gov/pubmed/25900386
Fluoroquinolone-induced acute interstitial nephritis
https://academic.oup.com/ndt/article/21/1/237/1819025
DETERMINATION OF THE EFFECTS OF CIPROFLOXACIN
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794863
Levofloxacin-induced rhabdomyolysis: a case report
https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-016-1004-6
REPRODUCTIVE
Antibiotics effect on testis tissue in rats
Assessment on the adverse effects of Aminoglycosides and Flouroquinolone on sperm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426151/pdf/ijrm-3-125.pdf
Boar spermatozoa successfully predict mitochondrial modes of toxicity
https://www.ncbi.nlm.nih.gov/pubmed/25624015
Reproduction Toxicology
The effect of ciprofloxacin on sperm DNA damage, fertility potential and early
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312808/pdf/vrf-3-131.pdf
Evaluation of ameliorative potential of supranutritional selenium on
https://www.ncbi.nlm.nih.gov/pubmed/27083143
Role of Mitochondria in Ciprofloxacin Sperm Cells
http://eprints.umsu.ac.ir/786/1/1933719113477482.pdf
Long-Term Effect of Ciprofloxacin on Testicular Tissue: Evidence for Biochemical and Histochemical Changes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850316/
RESIDUES
Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity
RESISTANCE
Covalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166900/pdf/fchem-02-00071.pdf
Reduction of hospital levofloxacin use is associated with a decrease in hospital-acquired fluoroquinolone-resistant Pseudomonas aeruginosa rates: An 11 year study
http://www.e-jmii.com/article/S1684-1182(15)00481-8/pdf
http://www.e-jmii.com/article/S1684-1182(15)00481-8/abstract
Quinolones: A Comprehensive Review
https://www.aafp.org/afp/2002/0201/p455.pdf
Concerns about extralabel fluoroquinolone use in food-producing animals
https://avmajournals.avma.org/doi/pdf/10.2460/javma.243.9.1242
Type II topoisomerase mutations in Bacillus anthracis
https://academic.oup.com/jac/article/54/1/90/746841
https://www.ncbi.nlm.nih.gov/pubmed/15190035
The Fluoroquinolones: How Long Will Their Utility Last?
https://www.ncbi.nlm.nih.gov/pubmed/15061660
http://www.tandfonline.com/doi/abs/10.1080/00365540410019039?journalCode=infd19
Association between fluoroquinolone resistance and MRSA genotype in Alexandria, Egypt
SAR
Investigating the fluoroquinolone-topoisomerase interaction by use of novel fluoroquinolone and quinazoline analogs use of novel fluoroquinolone and quinazoline analogs
http://ir.uiowa.edu/cgi/viewcontent.cgi?article=2403&context=etd
SERUM SICKNESS
Serum Sickness-Like Illness Associated with Ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC171716/pdf/aac00061-0258.pdf
SPECTROMETRY AND RELATED
7-{4-[(1,3-Benzodioxol-5-yl) methyl]-piperazin-1-yl}-1-cyclopropyl-6-fluoro-4-c
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394047/pdf/e-68-o2264.pdf
A Convergent Synthetic Route to (+)-Dynemicin A and Analogs of Wide Structural Variability
http://pubs.acs.org/doi/abs/10.1021/ja9703741
A Mild and Efficient Synthesis of 4-Quinolones and Quinolone Heterocycles
https://www.ncbi.nlm.nih.gov/pubmed/17458997
http://pubs.acs.org/doi/pdf/10.1021/jo070181o
Nonantibiotic Effects of Fluoroquinolones in Mammalian Cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf
Acyl Glucuronide DNA-adducts from Quinolones
https://pdfs.semanticscholar.org/78ee/bbe021406be4a6a23af1de4b16323f765fb5.pdf
Analysis of positions and substituents on genotoxicity of fluoroquinolones
https://www.ncbi.nlm.nih.gov/pubmed/27835744
A THEORETICAL-EXPERIMENTAL STUDY ON THE STRUCTURE AND ACTIVITY OF
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365236/pdf/MBD-07-301.pdf
Analytical profile of the fluoroquinolone antibacterials
https://www.ajol.info/index.php/ajb/article/view/58495/46839
A New Silver Complex with Ofloxacin
https://www.degruyter.com/downloadpdf/j/amma.2015.62.issue-2/amma-2015-0091/amma-2015-0091.pdf
An Adduct of Magnesium Sulfate with ciprofloxacin
http://scripts.iucr.org/cgi-bin/paper?S0108270196005343
Analytical methods for determination of new fluoroquinolones in biological matrices
https://link.springer.com/article/10.1007/s00216-011-5706-8
Analysis of the factors that significantly influence the stability of
https://www.ncbi.nlm.nih.gov/pubmed/19576385
Chemistry of 4-Hydroxy-2(1H)-quinolone. Part 1 - Synthesis and reactions
http://www.sciencedirect.com/science/article/pii/S187853521400015X
Biological activities of some Fluoroquinolones-metal complexes
HIGH-RESOLUTION MASS SPECTROMETRY APPLIED TO THE IDENTIFICATION OF TRANSFORMATION PRODUCTS OF QUINOLONES
http://diposit.ub.edu/dspace/bitstream/2445/50423/1/633709.pdf
DNA interaction, in vitro antimicrobial and SOD-like activity of copper
https://www.sciencedirect.com/science/article/pii/S0022328X11007388
Chapter- 7
http://shodhganga.inflibnet.ac.in/bitstream/10603/11316/10/chapter-%207.pdf
Characterization of intermediate compounds formed
http://onlinelibrary.wiley.com/doi/10.1002/rcm.3537/abstract
Validation of a liquid chromatography–tandem mass spectrometric method
https://www.sciencedirect.com/science/article/pii/S0003267004008529
Tandem mass spectrometric study of ciprofloxacin–poly(ethylene glycol)
https://www.sciencedirect.com/science/article/pii/S1387380608002108
Copper(II) complexes with norfloxacin and neutral terpyridines Cytotoxic,
https://www.sciencedirect.com/science/article/pii/S0277538712002112
Evaluation and degradation Chemistry of Orbifloxacin using LC-MS
https://www.ijsciences.com/pub/article/257
Ciprofloxacin induced neurotoxicity
https://www.ncbi.nlm.nih.gov/pubmed/25902267
Ciprofloxacin is an inhibitor of the Mcm2-7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791872/pdf/bsr033e072.pdf
Investigating the fluoroquinolone-topoisomerase interaction by use of
http://ir.uiowa.edu/cgi/viewcontent.cgi?article=2403&context=etd
Synthesis and Pharmacological Activity of Enoxacin Metal Complexes
http://www.journalijar.com/uploads/2013-11-01_110511_541.pdf
Confirmation of fluoroquinolone residues in salmon
https://www.fda.gov/downloads/Food/FoodScienceResearch/ucm071507.pdf
Synthesis, characterization, antimicrobial and cytotoxicity
https://link.springer.com/article/10.1007/s00706-015-1507-7
Spectroscopic Studies on the Binding of
https://pdfs.semanticscholar.org/6bfa/b49fd50684b13a85f0b6c7668987a8ad7d55.pdf
A comparative analysis of chromosomal aberrations in cultured human lymphocytes
https://link.springer.com/article/10.1007/s00204-009-0509-9
https://www.ncbi.nlm.nih.gov/pubmed/20049419
Evaluation of the levofloxacin release characters
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260945/pdf/ijn-7-001.pdf
Development and validation of LC ESI MS MS method for analysis of moxifloxacin and
https://www.ncbi.nlm.nih.gov/pubmed/26730550
Liquid chromatography-electrospray ionization-mass spectrometry
https://www.ncbi.nlm.nih.gov/pubmed/16272169
Synthesis, characterization and DNA binding of magnesium-ciprofloxacin
http://www.bf.uni-lj.si/fileadmin/groups/2747/Zaposleni/Natasa_Poklar_Ulrih/2006-NPU-JIB.pdf
Determination of Enantiomeric Impurity in Besifloxacin
http://onlinelibrary.wiley.com/doi/10.1002/chir.22042/abstract
Simultaneous Determination of the Residues of Fourteen
http://www.agriculturejournals.cz/publicFiles/56594.pdf
Rapid, sensitive and selective HPLC-MS/MS method for the quantification of topically applied besifloxacin in rabbit plasma and ocular tissues: Application to a pharmacokinetic study
https://www.ncbi.nlm.nih.gov/pubmed/26340560
http://download.xuebalib.com/xuebalib.com.28671.pdf
Electrochemical oxidation of fluoroquinolone antibiotics Mechanism
Photodegradation assessment of ciprofloxacin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750423/pdf/1752-153X-7-133.pdf
Liquid chromatography–tandem mass spectrometry
http://quimica.udea.edu.co/~carlopez/cromatohplc/hplc_ms_pharma_residues_2005.pdf
ANTIBIOTICS IN PLASMA by LCMS
http://www.eurekaone.com/wp-content/uploads/2013/05/258_LC79010en.pdf
Mass spectrometic study of speciation in aluminium fluoroquinolone solutions
https://www.ncbi.nlm.nih.gov/pubmed/22837440
http://journals.sagepub.com/doi/abs/10.1255/ejms.1183?journalCode=emsa
The Effect of Some Fluoroquinolone Family Members
https://pdfs.semanticscholar.org/2439/2c5c31fdfcf55478b7c6e62234e1fed0560b.pdf
KINETIC AND THERMODYNAMIC STUDIES OF MOXIFLOXACIN
http://www.ptfarm.pl/pub/File/Acta_Poloniae/2012/5/821.pdf
Evaluation and Degradation Chemistry of Orbifloxacin Using LC-MS
FQ and Metabolites in Chicken Muscles using MS-MS Barcelona Spain
http://diposit.ub.edu/dspace/bitstream/2445/50423/1/633709.pdf
FDA FQ residue
Defluorinated Sparfloxacin as a New Photoproduct Identified
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105763/pdf/ac001151.pdf
STATISTICS
An Update on Fluoroquinolones: The Emergence of a Multisystem Toxicity Syndrome
TENDON RUPTURE
DIAGNOSTIC FAILURE OF CIPROFLOXACIN-INDUCED SPONTANEOUS
https://www.ncbi.nlm.nih.gov/pubmed/21658328
Fluoroquinolones-Induced Tendinitis and Tendon Rupture in Kidney Transplant Recipients: 2 Cases and a Review of the Literature
Quinolone Ear Drops and Achilles Tendon Rupture
Fluoroquinolones and collagen associated severe adverse events: a longitudinal cohort study
THEORECTICAL MODELING
2D, 3D-QSAR and molecular
THYROID
Ciprofloxacin induced hormonal changes in the thyroid gland of
http://iosrjournals.org/iosr-jpbs/papers/Vol5-issue3/C0531218.pdf?id=4840
Determination of zabofloxacin in rat plasma by liquid chromatography with
WHAT IS A DNA ADDUCT
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618519/pdf/ijms-18-01870.pdf
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057941/pdf/nihms559280.pdf
- https://www.ncbi.nlm.nih.gov/pubmed/17574899
- https://search.proquest.com/openview/89f86c786c8827ae7045ce7b88e62f26/1?pq-origsite=gscholar&cbl=18750&diss=y
- https://dge.carnegiescience.edu/SCOPE/SCOPE_52/SCOPE_52_2.01_Beland_29-56.pdf
- http://journals.sagepub.com/doi/pdf/10.1177/019262330002800308
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950664/pdf/gkt1109.pdf
- https://www.hindawi.com/journals/jna/2010/929047/ref/
- https://www.sciencedirect.com/topics/neuroscience/dna-adduct
- http://pubs.rsc.org/en/content/articlelanding/2015/cs/c5cs00316d#!divAbstract
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