Fluoroquinolone drugs

Please note, the below list reflects drugs used in the United States, names and brands may differ in other countries and may be possibly found on: https://www.drugs.com or a type of Chat AI website.

The main fluoroquinolones used in the USA include generics along with the name brand - levofloxacin (Levaquin - was taken off market), ciprofloxacin (Cipro), ciprofloxacin extended-release tablets, moxifloxacin (Avelox), ofloxacin, gemifloxacin (Factive), delafloxacin (Baxdela), norfloxacin and Quinsair.

Key Differences Across Generations (see below drug lists):

1.Spectrum of Activity: Each generation added broader and more targeted coverage, especially against gram-positive bacteria and anaerobes.

2. Application: Later generations are used to treat a wider range of infections, including respiratory, urinary, gastrointestinal, and skin infections.

Quinolones Removed from U.S. Market (may not be complete list):

Cinoxacin; Clinafloxacin; Fleroxacin; Flumequine; Gatifloxacin; Grepafloxacin; Nalidixic acid; Pefloxacin; Temafloxacin (Omniflox); Sarafloxacin, Sparfloxacin; Zagam

Restricted Quinolones: Trovafloxacin

The below was updated November 2024 and may have omissions.

First Generation:

Flumequine(veterinary use), Oxolinic acid, Rosoxacin, Wintomylon

Structurally related first-generation drugs, but formally not 4-quinolones, include cinoxacin, nalidixic acid, piromidic acid, pipemidic acid

Second Generation:

Activon, Cipro, Ciprobay, Ciprofloxacin, Ciproxin, Enroxil, Enoxacin, Floxin, Janacin, Lexinor, Lo

First Generation:

Flumequine(veterinary use), Oxolinic acid, Rosoxacin, Wintomylon

Structurally related first-generation drugs, but formally not 4-quinolones, include cinoxacin, nalidixic acid, piromidic acid, pipemidic acid

Second Generation:

Activon, Cipro, Ciprobay, Ciprofloxacin, Ciproxin, Enroxil, Enoxacin, Floxin, Janacin, Lexinor, Lomefloxacin HCL, Maxaquin, Monos, Nadiflox, Nadifloxacin Acuatim, Nadixa, Nadoxin, Norfloxacin, Noroxin, Oxaldin, Peflacine, Pefloxacin, Penetrex, Proquin XR, Quinabic, Ruflox, Rufloxacin, Tarivid, Tebraxin, Uroclar, Uroflox

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Fluoroquinolone Ear Drops:

Cetraxal, Otiprio, Ciprodex, CiproHC

Otiprio, Floxin Otic (ofloxacin otic)

Xtoro (finafloxacin)

Fluoroquinolone Eye Drops:

Besivance (besifloxacin)

Cetraxal, Ciloxan (ciprofloxacin)

Exocin, Ocuflox (ofloxacin)

Iquix, Quixin (levofloxacin)

Moxeza, Vigamox (moxifloxacin)

Zymar (gatifloxacin)

Third Generation:
Balofloxacin, Gatiflo, Gatifloxacin, Grepafloxacin, Levaquin, Levofloxacin, Omniflox, Pasil, Pazucross, Pazufloxacin, Raxar, Sparfloxacin, Tequin, Temafloxacin, Tosufloxacin, Vigamox, Zagam, Zymar

Fourth Generation:
Alatrofloxacin, Avelox, Baxdela, Besifloxacin, Besivance, Clinafloxacin, Delafloxacin, Factive, Finafloxacin, Garenoxacin, Gatifloxacin, Gemifloxacin, Moxifloxacin, Ozex, Prulifloxacin, Quisnon, Sitafloxacin, Temafloxacin, Tosacin, Tosufloxacin, Trovan, Trovafloxacin

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Non-Fluorinated Quinolones:

Cinoxacin

Mictral

Miloxacin

Nalidixic acid

Nalidixate sodium

Nemonoxacin

Oxolinic acid

Ozenoxacin

Pipemidic acid

Piromidic acid

Rosoxacin

Fluoroquinolone Inhalers:

Quinsair (levofloxacin)

Intravenous (IV) in surgeries :

Ciprofloxacin (Cipro)

Levofloxacin

Moxifloxacin (Avelox)

Ofloxacin

Polycyclics:

Abufloxacin

Droxacin

Flumequine

Marbofloxacin

Mefloquine

Miloxacin

Ofloxacin

Oxolinic acid

Pazufloxacin

Prulifloxacin

Rufloxacin

Verbafloxacin

Fluoroquinolone drugs

Veterinary Fluoroquinolones

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Fluoroquinolone drugs

Veterinary Fluoroquinolones

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