Fluoroquinolone drugs

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Please note, the below list reflects drugs used in the United States, names and brands may differ in other countries and may be possibly found on: https://www.drugs.com or a type of Chat AI website.

The main fluoroquinolones used in the USA include generics along with the name brand  - levofloxacin (Levaquin -  was taken off market), ciprofloxacin (Cipro), ciprofloxacin extended-release tablets, moxifloxacin (Avelox), ofloxacin, gemifloxacin (Factive), delafloxacin (Baxdela), norfloxacin and Quinsair. 

Key Differences Across Generations (see below drug lists):

1.Spectrum of Activity: Each generation added broader and more targeted coverage, especially against gram-positive bacteria and anaerobes.

2. Application: Later generations are used to treat a wider range of infections, including respiratory, urinary, gastrointestinal, and skin infections.

Quinolones Removed from U.S. Market (may not be complete list):

Cinoxacin; Clinafloxacin; Fleroxacin; Flumequine; Gatifloxacin; Grepafloxacin; Nalidixic acid; Pefloxacin; Temafloxacin (Omniflox); Sarafloxacin, Sparfloxacin; Zagam

Restricted Quinolones:  Trovafloxacin

See FDA and EMA warnings on these drugs.

                               The below was updated November 2024 and may have omissions.