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Revised prescribing alert January 2024
https://www.gov.uk/government/news/mhra-introduces-new-restrictions-for-fluoroquinolone-antibiotics
European Medicines Agency’s (EMA) Fluoroquinolone Press Release 2019:
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European Medicines Agency’s (EMA) Fluoroquinolone Public Hearing 2018:
Summary -
Main points raised -
• Symptoms were life-changing and wide ranging.
• Patients were not given information about risks.
• Healthcare professionals were generally unaware of the range and severity of possible symptoms,
with the exception of Achilles tendon disorders
13 patient testimonies before the EMA starting at minute 14:15
https://www.youtube.com/watch?v=1vao8o5NGUc
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Pharmacovigilance Risk Assessment Committee (PRAC) Assessment Report 2018:
The following mechanisms may be supportive of a causal relationship between (fluoro) quinolones and tendon disorders:
Tendon disorders
Neurotoxicity
Neuropathies
Phototoxicity
Vasculitis
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