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DNA damage from Fluoroquinolone Antibiotics after only 3.61 minutes (in vitro)! A global problem?

 

All scientific publications since the 1980’s related to the following have been largely ignored thus far by the authorities: DNA damage, mitochondrial damage, accumulation of FQs in cells, nervous system damage, psychiatric disorders, reproductive defects, chromosomal abnormality, collagen destruction, aneurysms, HIF degradation, multi organ failure due to UGT, SULT and MRP 2 mutations, retinal detachment, cytotoxicity, genotoxicity, diabetes, muscle atrophy, P450/CYP 2E1 dysfunction. Please see our Research Project tab for additional studies in addition to what is on this page.

Please dedicate a few minutes to watch this important video: https://youtu.be/t_zBhMi5AYs

Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA [Scientific Reports 2017]

https://www.nature.com/articles/s41598-017-08392-1.pdf

Ciprofloxacin impairs mitochondrial DNA replication initiation through inhibition of Topoisomerase 2 [Nucleic Acids Res. 2018]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182158/

SUPPORTING STUDIES FROM OUR LIBRARY

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC174830/pdf/aac00096-0128.pdf

https://www.researchgate.net/publication/40848285_A_comparative_analysis_of_chromosomal_aberrations_in_cultured_human_lymphocytes_due_to_fluoroquinolone_drugs_at_different_expression_periods

https://www.ncbi.nlm.nih.gov/pubmed/21764262

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4571980/pdf/zbc22287.pdf

https://www.researchgate.net/publication/261759355_Pharmacokinetic_prediction_of_levofloxacin_accumulation_in_tissue_and_its_association_to_tendinopathy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760005/pdf/nihms-509241.pdf

https://www.ncbi.nlm.nih.gov/pubmed/8913349

https://www.ncbi.nlm.nih.gov/pubmed/18840496

https://www.ncbi.nlm.nih.gov/pubmed/20625181

http://eprints.umsu.ac.ir/786/1/1933719113477482.pdf

http://nmcth.edu/images/gallery/Editorial/xRZVmps_ambulkar.pdf

http://www.academicjournals.org/article/article1423846203_Arafa%20et%20al.pdf